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Positron Emission Tomography (PET)

Positron Emission Tomography is a scanning technique which detects chemical and physiological changes related to metabolism. This procedure produces 3-dimensional images of blood flow, chemical reactions and muscular activity in the body as they occur. It measures the intensely of the use (metabolization) of glucose, oxygen or other substances in the brain. This allows the neurologist to study the function of the brain. By measuring areas of blood flow and metabolism, the PET scan is used to locate the site from which a seizure originates.

The information provided by a PET scan is valuable in the diagnosis of seizure type and in the evaluation of a potential candidate for surgery. The PET scan tests brain metabolism, chemistry or blood flow by injecting a small amount of radioactive substance into the body. When this substance reaches the brain during the scan, a computer uses the recorded signals to create images of specific brain functions. A functional image of brain activity is important because functional changes are often present before structural changes in tissues. PET images may therefore demonstrate pathological changes long before they would be evident by other scanning techniques.


Before a PET Scan

    • Your child not eat or drink anything four to six hours prior to the exam.
       
    • Your child should wear comfortable clothing.
       
    • Your child shoudl take all prescribed medication(s) as usual unless instructed otherwise by the physician.
       

During a PET Scan
    • Before the scan, a small amount of radioactive tracer will be injected or inhaled by your child. The tracer is a compound, such as sugar, "labelled" with a short-lived radioisotope.
       
    • Following the injection, your child will be asked to rest for approximately 30-45 minutes while the substance reaches the brain.
       
    • The technologist will place your child on a scanner table.
       
    • His/her head will be in a special head rest and immobilised using foam blocks or a special mould shaped for your child.
       
    • It is important for you child to lie completely still.
       
    • The scanner table will slowly pass through the PET scanner. Your child's head will be inside the large, doughnut-shaped machine. The scanner detects the radioactive material to produce a computer image of your child's brain.
       
    • Scanning time is approximately 1-2 hours.
       
drawing by Karen Chan

After a PET Scan
    • There are no after effects from the injection or the PET imaging.
       
    • Your child can resume normal activity immediately after the PET scan is completed.
       
    • The PET scan will be reviewed by a radiologist or nuclear medicine technologist who will report to your child's physician. The physician will then make a follow-up appointment to discuss the results with you.
       

Personnel
      Nuclear Medicine Technologist
        • operates cameras which detect and map the radioactive tracer in the patient's body to create an image on the computer monitor
        • explains test procedures to patients
        • prepares the radiopharmaceutical and administer it orally or through injection.
           
      Doctors
        • interpret the results.
           


Availability
    • Clarke Institute of Psychiatry, Toronto, Ontario
      416-535-8501
       
      The cost of the test is covered by research grants to the institute.
       
       
    • McMaster-Chedoke Hospital, Hamilton, Ontario
      905-521-2100
       
      The cost of the test is covered by the hospital.
       
       
    • Montreal Neurological Institute and Hospital, Montreal, Quebec
      514-398-5358
       
      The test costs $700. You must pay for the test but you will be reimbursed fully by the Ontario Health Insurance Plan (OHIP).
       
       
    • University of British Columbia, Vancouver, British Columbia
      604-822-2211 (general directory)
       
       
    • Contact the Epilepsy Foundation (of America) for locations in the USA.
      301-459-3700
      www.efa.org
       
      The test costs approximately US$1700.
      It is not covered by insurance: the individual pays for it.
       
       

Important Considerations
      • Pregnant women should not undergo a PET Scan because of the radioactive isotopes used.
      • If your child is or may be pregnant, inform your doctor.


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Last Modified: 07/17/2006 11:17:51 AM